The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here
Real Scientific Hemp Oil™ is the world’s leading hemp CBD oil brand. All RSHO™ products are derived from non-GMO hemp, scientifically extracted using a solvent-free CO2 process, and quality-certified through our Triple Lab Testing™ process to bring the powerful natural benefits of hemp CBD. It’s a science that we take great pride in day in and day out.

Manufacturers are free to sell what they consider as the best form of hemp oil CBD extract. This being the case, there are a lot of companies taking advantage of the CBD oil demand thus are making products that don’t contain enough or any CBD at all. All they care about is making profits by sourcing the cheapest CBD oils they can find on the market.
Dogs and cats are known for their powerful sense of smell. They typically don’t like having something new added to their food, making supplementing their diets to ease health issues challenging. However, CBD products for pets take that challenge into account. Developed by dedicated veterinarians, they’ve been designed to pass the taste and smell test.
Cristina Sanchez, a molecular biologist from Complutense University in Madrid, Spain, explains to CannaInsider, “cells, not only cancer cells, but every cell in our body can die in different ways. One could be similar to an accident, a car accident, a traumatic death which is called necrosis. And there is another way to die which is a clean death and by clean I mean no inflammation of the surrounding tissues. And this cancer cell death is called Apoptosis. And when someone’s dealing with anti-tumor compounds, one wants this particular kind of death to happen because the other one is associated to inflammatory processes and things like that that you don’t want in a patient.”
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
Unregulated markets come with some obvious risks; lack of oversight, false claims, the potential for dangerous pesticides and contaminants. Cannabis, in states where it’s legal, is regulated. Sold in state-licensed stores (akin to states controlling liquor stores, except with higher taxes and much stricter regulations) aka dispensaries, you can be confident that the CBD-dominant cannabis tinctures, topicals, vapes, and edibles on shelves are accountable to purity and accuracy tests.

Everybody has different medical needs, because of this Medix CBD hemp oil tinctures are available in different dosages ranging from 100mg – 4,500mg per bottle. The reason for such a large difference in CBD concentrations between the lowest strength bottle and the highest strength bottle is because we offer a vast and wide selection of CBD hemp oil tinctures to meet the needs of people with different medical goals.
NuLeaf Naturals is headquartered in Colorado, but we ship anywhere in the US. All of our organic CBD oil products will be sent to you via USPS, FedEx, or UPS and should arrive in just 2-3 business days. We offer special pricing options for bulk orders. If you sell health and wellness products and would be interested in promoting medical cannabis oil, consider becoming a wholesale CBD oil partner with us.

Some industry insiders argue that organic, pharmaceutical-grade ethanol, which is a grain alcohol, is optimal and eliminates certain toxins and residues in the raw plant material itself. But others say that while this extraction method yields a high amount of cannabinoids and is GRAS (Generally Recognized as Safe) for human consumption, it destroys the plant’s waxes, leading to a less potent oil.

Typically, our CBD hemp oil products come in three potency levels. With our lowest concentration of CBD per serving, between 1 and 3 mg, our hemp oil tinctures are an ultra portable way to add small amounts of CBD to your system throughout the day. Our medium range products, like our RSHO™ Liquid and our hemp oil capsules, are excellent once or twice daily additions to your diet, offering 31 and 25 mg of CBD, respectively. Finally, our RSHO™ oral applicators provide our highest levels of CBD, between 50 and 120 mg, depending on the label color you choose.
But, and there’s always a “but” when it comes to weed in America, unless you’re buying cannabis CBD in a state where weed is recreationally legal or have a medical card in a legalized state, you’re shopping in the unregulated market that is industrial hemp CBD. (Full disclosure: I've worked with restaurants to launch hemp-CBD drinks and am the co-founder of Nice Paper, a site about cannabis.)
The human body has an endocannabinoid system — a natural system that maintains homeostasis or balance, in the body. The endocannabinoid system has CB1 and CB2 receptors. These are found throughout the body. CB1 receptors are generally located in the central and peripheral nervous system and CB2 receptors are generally found in the brain, immune system, and gastrointestinal system. CBD binds to these receptors creating changes and effects in the body

CBD is a safe, long-term aid which is why it has gained such momentum and why our customers are turning to it for relief. CBD, scientifically known as cannabidiol, is a non-psychoactive, organic compound found in the hemp plant. When it interacts with the body’s endocannabinoid system, CBD provides powerful health benefits without the side effects of conventional drugs.
It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.

CBD is a safe, long-term aid which is why it has gained such momentum and why our customers are turning to it for relief. CBD, scientifically known as cannabidiol, is a non-psychoactive, organic compound found in the hemp plant. When it interacts with the body’s endocannabinoid system, CBD provides powerful health benefits without the side effects of conventional drugs.
Available in 3 labels (Green, Blue, and Gold), our RSHO™ provides a high-CBD hemp oil supplement with minimal processing. Because of its high concentration of CBD, RSHO™ is our most expensive line of products. In the 3 gram tubes, our Green Label contains 300 mg of CBD for $69, the Blue Label has 510 mg for $149, and our refined Gold Label tops out at 720 mg for $179.
It depends on the testing standards of the lab administering your drug test. Most companies only search for the cannabinoid THC, which is the main psychoactive component of the marijuana plant. While Medterra products are THC free, there are some testing facilities that check for a spectrum of cannabinoids and could trigger a positive drug test. By law, you are allowed to ask the facility what cannabinoids they test for. If you are uncomfortable with that, you can call and ask anonymously. We suggest contacting the testing facility if there is any concern.

Everybody has different medical needs, because of this Medix CBD hemp oil tinctures are available in different dosages ranging from 100mg – 4,500mg per bottle. The reason for such a large difference in CBD concentrations between the lowest strength bottle and the highest strength bottle is because we offer a vast and wide selection of CBD hemp oil tinctures to meet the needs of people with different medical goals.

We’ve systematically sought out the most beautiful and healthy hemp cultivars for our raw ingredients used in CBD oil manufacturing, and we always test for purity and potency. Hemp, because of its innate ability to thrive easily, doesn’t require pesticides (the aromatic terpene compounds in hemp can actually act as natural pesticides), fertilizers, or herbicides in its cultivation, and requires much less water than standard commercial farming. The hemp we use is grown under the same methods and standards of organic farming.


As of now, there are only 9 states (and Washington, D.C.) that permit the use of marijuana on a recreational level. This means that, depending on where you live, it may or may not be possible to just walk into a dispensary and ask for a bottle of fine quality CBD oil. Also, some of those 9 states (even though they are recreationally legal for weed) may actually require you to obtain a medical marijuana card or a physician’s recommendation for CBD oil. If this is the case, though, it’s really no biggy as getting an online recommendation is incredibly easy nowadays, and can usually be done in minutes..
CBD testing shouldn’t just tell you what’s in a CBD oil, which is usually CBD along with a carrier oil like grapeseed oil and maybe some other essential oils for flavor. It should also let you know what’s not in the package. Thorough testing can confirm that the oil you’re buying is not only real CBD, but that it’s free of contaminants like pesticides and synthetic CBD substitutes.
I have my MMC but don’t care for the Trustik Pod 800mg Sativa for use with my vape pen. I don’t like the high feeling, plus need to be able to drive to my doctors appts. I want to try CBD again. Had tried Charlotte’s Web by Stanley Brothers of Colorado and it helped a little but not enough to stop narcotics I am on. Would the CBD products from dispensary be stronger than what I tried before?

Typically, our CBD hemp oil products come in three potency levels. With our lowest concentration of CBD per serving, between 1 and 3 mg, our hemp oil tinctures are an ultra portable way to add small amounts of CBD to your system throughout the day. Our medium range products, like our RSHO™ Liquid and our hemp oil capsules, are excellent once or twice daily additions to your diet, offering 31 and 25 mg of CBD, respectively. Finally, our RSHO™ oral applicators provide our highest levels of CBD, between 50 and 120 mg, depending on the label color you choose.
Many users of CBD oil have reported a number of benefits to adding the supplement to their daily lives. From experiencing feelings of calm and relaxation to assisting in the relief of some symptoms associated with chronic illness, anxiety, and inflammation, CBD oil is certainly earning its fast-growing reputation as a powerful support for wellness.
CBD oil has become the general term used when referring to these different oils, but while they derive from the same plant, they are actually quite different. Cannabis CBD oil sometimes contains high quantities of THC (between 5%-10% or even higher), while hemp CBD oil usually contains less than 2% THC. Industrial hemp, on the other hand, contains even less THC (under 0.3%), and therefore can be sold, bought, consumed and shipped legally in some U.S. states.
The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from organic hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.
To add to the challenges, brands in the CBD space are struggling to verify their own products. Laura White, founder of Soul Addict, started a CBD line after she found it helped her with crippling anxiety. Wanting to create a reliable product in both purity and potency, she’d test on top of the farm’s tests and kept running into the same problem: The lab results didn’t match. When White finally found a farm that had accurate tests, she’d partner with them. A few years later, Soul Addict now sources all its CBD through small, family-run farms in Colorado and White is in the process of integrating her own crops from North Carolina. The lesson she learned? Brands should be constantly testing their product to verify their farms’ reports.
CO2 extraction is one of the most common ways CBD is extracted from the hemp or cannabis plants. This method uses expensive equipment that adjusts temperature and pressure to extract the cannabinoids from the plant material, without damaging them. The other common method is to use solvents like ethanol or butane to extract the plant material. These solvents have to be burned off the final product which may damage the cannabinoids or terpenes in the process. There is also a risk that these solvents may not have burned off completely and could end up in your end product.
Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity. But THC metabolites are stored in the fat cells of your body, building up over time. If you ever need to take a drug test, this could create an issue for you.
Unregulated markets come with some obvious risks; lack of oversight, false claims, the potential for dangerous pesticides and contaminants. Cannabis, in states where it’s legal, is regulated. Sold in state-licensed stores (akin to states controlling liquor stores, except with higher taxes and much stricter regulations) aka dispensaries, you can be confident that the CBD-dominant cannabis tinctures, topicals, vapes, and edibles on shelves are accountable to purity and accuracy tests.
Generally, CBD oil is made by combining an extract with a carrier fluid or oil. This question is best answered by looking at how the CBD oil was extracted. CBD oil can be extracted using CO2 systems or by using chemical solvents. Both methods produce a CBD oil byproduct that is then combined with a fluid like MCT oil, coconut oil, or olive oil so that it can be delivered to the body. Always check to make sure you know the CBD content of the products you purchase.

CBD may be best known for its relaxing, calming effects. CBD reduces autonomic arousal, having the inverse effect of THC on the body. CBD’s anti-anxiety effect is why many in the cannabis community talk about how CBD relieves paranoia, although that is not scientifically proven yet. CBD is also known for its anti-nausea and pain relieving effects. It really depends on why your body’s specific needs and the quantity in which you take CBD.
Honestly, you can find CBD oil just about anywhere. Went on a cross country road trip this summer and was laughing at the “CBD for sale here” signs in these tiny little nothing towns. My experience? Buy the good stuff online. I’ve heard consistently good things about Elixinol, Purekana and green roads. Honestly don’t know what the hell this stuff is that they’re selling all over the country, but I’d stay away from it
“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.
NuLeaf Naturals is headquartered in Colorado, but we ship anywhere in the US. All of our organic CBD oil products will be sent to you via USPS, FedEx, or UPS and should arrive in just 2-3 business days. We offer special pricing options for bulk orders. If you sell health and wellness products and would be interested in promoting medical cannabis oil, consider becoming a wholesale CBD oil partner with us.
×