The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here


“Barely in its infancy, the CBD medical market is still largely unregulated; quality control is meager at best, and consumers are largely unaware what to look for when shopping …,” explains Carlos Frias of the Texas Wellness Center. Frias, who has been with the cannabis industry for more than 15 years, has seen, firsthand, the shadiness that exists in the CBD market.

There is a lot to be hopeful for as legalization marches forward and as cannabis becomes more widely accepted for its medicinal purposes. Unfortunately, with cannabis and CBD still listed as schedule one substances, research is limited and many medical professionals still remain in fear to discuss or endorse medical cannabis for something like cancer. As of March 2015, over 15,000 patients in the state of Colorado reported severe nausea or cancer as their reporting condition for their medical card. Organizations like Project CBD, Realm of Caring, and CannaKids provide resources and connect families who seek cannabinoid therapy for their illnesses. According to a 2016 estimate by procon.org, there are over 2.5 million medical marijuana users in the United States. This number grows every year as more states legalize access to medical cannabis and it’s becoming harder for the mainstream medical community to ignore this growing group of people.


When it comes to CBD oil, cheaper is most certainly not always better because the production of quality CBD oil just isn’t cheap. CO2 extraction utilizes complex equipment and a high level of expertise as opposed to the cheaper and easier chemical extraction processes that can leave residue from toxic solvents like butane, propane, and ethanol in the CBD oil. While the CO2 extraction will generally lead to a higher price tag, it does insure quality, purity, and potency – especially when used to extract CBD oil from hemp that has been organically grown in the United States.

Although it is better to consume CBD isolate than nothing at all, it may not offer you the same range of positive effects as full spectrum CBD powder. You still receive an adequate amount of CBD, but you also consume dozens of beneficial cannabinoids and terpenes. As a result, your body will receive more than enough vitamins, minerals, and nutrients. Not only will full spectrum CBD powder relieve pain, reduce stress and help you sleep, but it can also keep your body strong, fit and healthy. 


Some people don’t mind, or even enjoy the natural taste of hemp oil tinctures. For those who are bothered by the distinctive herbal taste of hemp extract, a flavored CBD oil tincture may be better. We’ve selected a variety of both flavored and unflavored CBD oil tinctures in this roundup, and many of the brands selected offer multiple options. If you still can’t stand the flavor of CBD tincture, consider another option like CBD gummies or capsules. Topical CBD is another popular choice, especially if you’re treating body aches or certain skin problems.
Others companies use organic, pharmaceutical-grade ethanol to process CBD. The ethanol, which is essentially grain alcohol, is used to remove unneeded toxins and residues from the base hemp plant. This method of extraction is generally considered to be the extraction process that yields the highest amount of cannabinoids among the different refinement processes as well as being considered the safest method of extracting CBD for human consumption.
Available in 3 labels (Green, Blue, and Gold), our RSHO™ provides a high-CBD hemp oil supplement with minimal processing. Because of its high concentration of CBD, RSHO™ is our most expensive line of products. In the 3 gram tubes, our Green Label contains 300 mg of CBD for $69, the Blue Label has 510 mg for $149, and our refined Gold Label tops out at 720 mg for $179.

Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.

Look for brands who source their cannabinoids from organic-certified, hemp-grown farms in pristine regions of Europe. “The German regulatory system is strict and enforced, providing confidence in the superiority of their harvest, processes, and extraction quality,” adds Moriarity. Organic hemp grown in Europe must also adhere to EU’s strict organic standards, which are stricter than in the U.S. and highly audited. Also, look for ingredients that are certified organic and wildcrafted.
I said the stuff you see advertised ON THE SIDE OF THE ROAD – I wasn’t referring to anything that’s “not from a dispensary”. Where I live (outside Galveston TX) there are a few places that advertise “CBD Sold here” and I’ve tried it, was a complete waste of money. I have used Green Roads and I know for a fact it is a good CBD oil that has great results. Just can’t really afford to buy a bottle every two weeks. I had an MMJ card when I lived back in PA but unfortunately Texas doesn’t have a medical program
The amount of milligrams of CBD you should take depends on your specific reason for taking CBD. If you are using CBD to treat chronic pain, you might take a much higher dose than someone who would be using CBD for general wellness reasons. Google search for your specific condition or reason for taking CBD to find the dose that is appropriate for you. You can take CBD in high qualities, so feel free to test out different dosages and see how your body reacts. A standard dose of CBD is 10 mg once a day, but this varies so widely because each individual is different so this can’t be taken as a recommendation for you.

Hemp grown for industrial purposes may be treated with harsh chemicals and solvents in the manufacturing process, leaving any resulting hemp oil unfit for consumption. Because our hemp is grown in ideal conditions to produce the best CBD products, we never use harmful chemicals in our extraction process. Instead, we extract our hemp oil using supercritical CO2, which the FDA considers GRAS or generally regarded as safe. This chemical process allows us to ensure that our CBD hemp oil supplements are always free from contamination to best protect the health of your family.

CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
Dixie Botanicals® all-natural hemp oil products provide the holistic benefits of CBD in convenient and portable supplements to fit your active, mobile lifestyle. Dixie Botanicals® products are derived from non-GMO hemp, scientifically extracted using a solvent-free CO2 process, and quality-certified through our Triple Lab Testing™ process to ensure the safety and reliability of every product, every time.
We’re proud to be among the few companies that provide lab analysis  for their products. Results of our lab tests are visible for anyone who wants to see what Elixinol™ contains, and that is 18% CBD, along with all the synergistic cannabinoids in the original plant. We produce a wholesome extract, not an isolate nor a synthetic product, because our focus is on delivering a pure, highly qualitative CBD oil, and not a cheap product with zero benefits for your health.

There is a growing number of medical cannabis dispensaries offering CBD-rich products in the U.S. Most physical dispensaries are required to operate under state health and safety standards set by law. The state conducts background checks on owner and staff, and dispensaries must meet security requirements and strict licensing guidelines. When buying hemp-based CBD oil (low in THC or/and CBD) you will not need a card, however, to purchase cannabis plant-based CBD oil patients need to be certified by a doctor who is part of their continuing care, and who’s registered with the state’s medical-marijuana program. That, however, applies only to those living in states that have passed medical marijuana laws. It is important for one to visit the dispensaries and get as much information as to whether their products have been tested and undergone clinical trials.


Real Scientific Hemp Oil™ (RSHO™) is our CBD hemp oil in its most unadulterated form. A thick, viscous oil, RSHO™ contains high levels of CBD, up to 190 mg, as well as essential vitamins, minerals, fatty acids, and other trace cannabinoids. Perfect for those looking for the highest concentration of CBD in their supplement, our pure CBD hemp oil comes packaged in an easy to measure oral applicator for accurate, mess-free servings.
It is a strict violation of the Food and Drug Administration DSHEA guidelines to make medical claims about the efficacy of CBD products in the treatment of any medical condition or symptom. Although preliminary research has shown tremendous promise of CBD oil helping people in pretty remarkable ways, legitimate CBD companies will refrain from making any direct medical claims. Be very wary of companies that defy this guideline, because if they disregard this particular rule, what other rules are they willing to ignore?
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