The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here
Mary's Nutritionals, CBDrx/Functional Remedies, Irie Hemp Company and CW Botanicals.  All of these brands represent the highest quality in domestically grown and produced CBD rich hemp extracts. This is cannabis oil that is manufactured utilizing base extracts from hemp grown in Colorado or Oregon, produced specifically for CBD extraction in accordance with the 2014 Farm Bill.
Good day everyone. I’m the father of a daughter diagnosed with hydraencephaly. It’s a life limiting condition with many other issues that accompany it. I’m eager to try CBD products in hopes of helping with her what they call neuro storms. I’ve done some research and have come to the conclusion that there’s many different products made from different parts of the plant. I live in Michigan and laws state CBD to be legal for sale (less than .03%. THC) After reading this and skimming through the comments I think that something stronger than this would be the answer. I hate giving my daughter pharmaceutical drugs (although one hormone she takes is life saving and I won’t discontinue that unless by some miracle CBD would). I’m desperate to find a natural answer. I would be forever grateful for any and all opinions and information that will help guide me to a better quality of life for my beautiful daughter. My hopes lie within your wisdom. Thank you for taking the time to read and/or respond. Have an excellent day!
Correct Answer: Each batch of flower AND finished product should be tested by a state certified testing facility for potency, legality and safety. These test results should also be made available to any patient that requests them. These tests should certify 3 things: the amount of CBD contained in the product, the amount of THC in the product (the starting hemp plant material must test below 0.3%), and the lack of mold or toxic pesticides.
I was having excruciating nerve pain. I couldn’t sleep, had a hard time even holding my phone even. I was at my wits end. Justin from Kats sent me a bottle of the 1020 full spectrum CBD. I was told that it would take a few days to build up in my system. I took 5 drops the first time and felt it within 10-15 minutes. I was even able to sleep. I was so thankful that it worked instantly. On day 5 it was even better! I now use the 600 mg daily and use the 1020 on high pain days. I’d recommend this to anyone and I’m super excited to try the new CBD products that’s to come!
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.

There are over 85 cannabinoids that make up the marijuana plant. The most popular and well known of these is tetrahydrocannabinol, or better known as THC. THC is a psychotropic cannabinoid that causes a high when inhaled or ingested. CBD has no THC. This means those dealing with various forms of pain and depression can safely use CBD to curb negative effects on the body without having to turn to prescription pharmaceuticals.
HoneyColony and its materials are not intended to treat, diagnose, cure or prevent any disease. All material on HoneyColony is provided for educational purposes only. Always seek the advice of your physician or another qualified healthcare provider for any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health related program.
There are SO many CBD brands out there! We carry only those that we have tried ourselves, and had tested at a 3rd party lab. We want to make sure that all the good things (like an accurate amount of cannabinoids) are in there! And that all the not so good things (like psychotropic compounds, heavy metals, and pesticides) are not there. We also choose to work with those companies that service their customers just as we do. Here are some of our favorite (and best selling!) brands:
CBD Kratom is proud to operate in Chicago, St. Louis, Dallas and Los Angeles! We’re your one-stop shop for CBD oils and edibles, hemp products, various strains of Kratom and lots more. We carry over 45 strains of Kratom and we are always looking to add products. We’ve got CBD gummies, jollies, peanut butter, vape and more. We offer you the largest selection of CBD and Kratom products in Chicago and they’re at affordable prices. Did we mention the staff here at CBD Kratom is just as awesome as the products we carry? If you can’t find what you’re looking for we’ll be sure to help you find it!
Cannabidiol (CBD) is one of dozens of non-psychoactive cannabinoids found in the hemp plant. Cannabidiol, and all the other cannabinoids, were patented by the United States Government in 2003 as neuroprotectants and antioxidants (Patent No. 6,630,507). Cannabinoids are characterized by their ability to act on the cannabinoid receptors that are found throughout the body. CBD and other cannabinoids are naturally occurring compounds that display potent anti-inflammatory and pain-relieving properties. They can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.
Is it full-spectrum? Full-spectrum is the use of the whole hemp plant vs. an isolate which extracts the CBD from the plant. Using marketing terms like “pure” and “all natural,” isolates are sometimes not hemp at all and synthesized in a lab. While the efficacy of full-spectrum is debated in the scientific community, anecdotes and a study in Israel favor full-spectrum. In addition to potential benefits, there’s another reason you should be buying the whole plant: contamination. Chen notes that isolates are harder to trace back to origin and can be straight-up fake. Overseas lab-made isolates are cheaper than domestic versions, making the potential for contamination high. Utah recently grappled with synthetic CBD when 52 people became sick from an isolate. While isolates can be legitimate (FDA-approved Epiliodex is an isolate), you’re going to have to spend more time researching the brand’s products and practices. Put it this way, if you could get your vitamin C from Sunny D or fresh squeezed OJ, which would you prefer?
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.

All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).


Finally, most of the products below simply contain hemp oil extract, mixed with a neutral carrier oil like hemp seed oil or coconut oil. While hemp seed oil is packed with nutrition, CBD brands are beginning to offer supplements with added ingredients that may offer additional benefits. We’ve included the complete ingredients of every product. Be sure to avoid any known allergies and investigate the pros and cons of any additional ingredients.
CBD oil is a refined oil rich in the cannabinoid molecule cannabidiol, more commonly known as CBD. Unlike it’s more infamous cousin, THC, CBD is not psychoactive, meaning it doesn’t cause the traditional high associated with cannabis. And while CBD oil can be sourced from any cannabis plant, it is commonly derived from agricultural hemp—cannabis plants bred to express less than 0.3% THC and thus have no intoxicating potential.
CBD Kratom is proud to operate in Chicago, St. Louis, Dallas and Los Angeles! We’re your one-stop shop for CBD oils and edibles, hemp products, various strains of Kratom and lots more. We carry over 45 strains of Kratom and we are always looking to add products. We’ve got CBD gummies, jollies, peanut butter, vape and more. We offer you the largest selection of CBD and Kratom products in Chicago and they’re at affordable prices. Did we mention the staff here at CBD Kratom is just as awesome as the products we carry? If you can’t find what you’re looking for we’ll be sure to help you find it!
Is it full-spectrum? Full-spectrum is the use of the whole hemp plant vs. an isolate which extracts the CBD from the plant. Using marketing terms like “pure” and “all natural,” isolates are sometimes not hemp at all and synthesized in a lab. While the efficacy of full-spectrum is debated in the scientific community, anecdotes and a study in Israel favor full-spectrum. In addition to potential benefits, there’s another reason you should be buying the whole plant: contamination. Chen notes that isolates are harder to trace back to origin and can be straight-up fake. Overseas lab-made isolates are cheaper than domestic versions, making the potential for contamination high. Utah recently grappled with synthetic CBD when 52 people became sick from an isolate. While isolates can be legitimate (FDA-approved Epiliodex is an isolate), you’re going to have to spend more time researching the brand’s products and practices. Put it this way, if you could get your vitamin C from Sunny D or fresh squeezed OJ, which would you prefer?
I cannot personally vouch for most of the brands on Amazon currently vs. most of the merchants on our page here, but I include Amazon as a resource for the folks that are comfortable shopping via that platform. You can also find my beginners guide, The Cannabis Oil Companion on Amazon in both paperback and Kindle.  *We have been having some issues with our Amazon widget not displaying below intermittently in certain browsers, trying to troubleshoot this behavior, we apologize if this is not rendering for you.  There is also a text link to Amazon's hemp oil section listed below.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
Hello! I do not have a response regarding what you should take, BUT want you to know I am exactly where you are! Three level lumbar fusion on 02/05/18, no staples thank goodness (they used glue), but am weaning myself off of pain meds ( I don’t like their side effects, as you stated). Weaning off the pain meds leaves me susceptible to flare ups when I do my PT or go for my daily walks three times a day. I surely hope someone answers the question you posed, as I would like to know! Wishing you the best of luck in your recovery! Stay strong!

It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.

In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
No matter who you shop from make sure you know where the company of your choice gets their hemp from. Hemp naturally pulls toxins from the soil so in turn it could actually cause more harm than good. You want hemp grown in good clean, organic, healthy bio diverse soil. Sunshine Marketplace does just that. Their products are organic, high in cbd, has added vitamin D and their Funk has added mineral salts for an added health bonus. Please always shop from a reputable company.
Look for brands who source their cannabinoids from organic-certified, hemp-grown farms in pristine regions of Europe. “The German regulatory system is strict and enforced, providing confidence in the superiority of their harvest, processes, and extraction quality,” adds Moriarity. Organic hemp grown in Europe must also adhere to EU’s strict organic standards, which are stricter than in the U.S. and highly audited. Also, look for ingredients that are certified organic and wildcrafted.

The first thing you need to know about selecting a CBD Oil product is that they can be made from extracts from either Hemp Plants or Marijuana Plants.  And, currently, those from marijuana plants are not legal in many states, nor can they be shipped across most state lines.  So, for Fully Legal CBD Oil products in ALL STATES, you want to be sure you’re selecting Hemp Based Products (note:  all Highland Pharms products are from Hemp).
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