CBD oil is a refined oil rich in the cannabinoid molecule cannabidiol, more commonly known as CBD. Unlike it’s more infamous cousin, THC, CBD is not psychoactive, meaning it doesn’t cause the traditional high associated with cannabis. And while CBD oil can be sourced from any cannabis plant, it is commonly derived from agricultural hemp—cannabis plants bred to express less than 0.3% THC and thus have no intoxicating potential.
“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.
When buying industrial hemp CBD, i.e. everything you see outside of a state-licensed dispensary, all bets are off. Because the legality of industrial hemp is in flux, companies that use hemp CBD operate in a gray market with no oversight. Nick Mosely, Chief Science Officer of a testing lab in Washington explained that “everything currently on the market for interstate CBD sales is unregulated.” And product labels can be wildly different from what's actually contained in the product. Multiple studies of CBD oil sold online have repeatedly exposed brands that misrepresent purity and CBD dosage levels.

Hi Tadd, thanks for the detailed comment on our site. As you said you will probably need something that contains a stronger substance but with cases like yours its extremely important to get the right dosage. Hydraencephaly is a vary rare case and something you should consult with medical marijuana doctor. You should also try to contact charlotte’s web, they might be able to assist. Hope this helped


I appreciate your efforts in writing this article & don’t mean to disparage you, but there’s so much information that goes into this discussion & people need to be prepared ahead of time. One very important note is to make sure that nothing in the CBD will be contraindicated with many prescription medications, especially for diabetes, hypertension, blood thinners & anti-platelets for example. If a company’s website says their formula is a “proprietary blend”, call before you buy, please!
It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.

I am in a pain management program and I was told that they test for cannabiniols across the board so even though there is no THC I could still test positive and be kicked out of the program. This is so unfair because CBC has been the best thing for PTSD anxiety and depression instead they would rather me be on multiple drugs with multiple bad side effects. Even though it’s legal in KY we re still in the dack ages. Any thoughts or help on this I would greatly appreciate how to get around it.
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Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
When it comes to CBD oil, cheaper is most certainly not always better because the production of quality CBD oil just isn’t cheap. CO2 extraction utilizes complex equipment and a high level of expertise as opposed to the cheaper and easier chemical extraction processes that can leave residue from toxic solvents like butane, propane, and ethanol in the CBD oil. While the CO2 extraction will generally lead to a higher price tag, it does insure quality, purity, and potency – especially when used to extract CBD oil from hemp that has been organically grown in the United States.
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