The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here
Mary's Nutritionals pioneered the first CBD transdermal patch, after using this technology with great success in their Medicinals line of marijuana based products, that have been available in certain NW legal states for many years now.  Mary's is an established name, now bringing to market high quality cannabis oil products sourced from domestic Colorado grown hemp.
When you are purchasing CBD Oil Products, you have two options: Full Spectrum CBD or Isolated (regular) CBD. Full Spectrum CBD, as Hemp Oil, contains every Cannabinoid present in the Hemp (Cannabis Sativa) plant. This means Cannabidiol, Cannabicyclol, Tetrahyrdocannabivarin, and Cannbichromevinaric acid, to name a few. In Full Spectrum CBD Oil, there is nothing held back or left out. On the other side CBD Isolate contains pure CBD compound, which has a more flexible legal status as well no taste, color or strong odor as Full Spectrum CBD Oil.
Phyto Plus Whole Plant Hemp Cannabidiol extracts, naturally grown, free from insecticides, pesticides and non GMO. Worldwide same day shipping from the Netherlands. Produced with safe, solvent residue free, super critical CO2 extraction, the cleanest extraction method in the industry. If you are wondering where to buy pure cbd oil online in Europe, Phyto Plus is a great option. 
I will continue to use bluebird botanical products loyally. Their customer service is exceptional. Their products are of exceptional quality and reasonably priced. Due to the dedication of their staff, I have been given back something I thought was lost to me: HOPE. I cannot thank BlueBird enough for their dedication to sharing a product that improves the quality of life for others.

Is it full-spectrum? Full-spectrum is the use of the whole hemp plant vs. an isolate which extracts the CBD from the plant. Using marketing terms like “pure” and “all natural,” isolates are sometimes not hemp at all and synthesized in a lab. While the efficacy of full-spectrum is debated in the scientific community, anecdotes and a study in Israel favor full-spectrum. In addition to potential benefits, there’s another reason you should be buying the whole plant: contamination. Chen notes that isolates are harder to trace back to origin and can be straight-up fake. Overseas lab-made isolates are cheaper than domestic versions, making the potential for contamination high. Utah recently grappled with synthetic CBD when 52 people became sick from an isolate. While isolates can be legitimate (FDA-approved Epiliodex is an isolate), you’re going to have to spend more time researching the brand’s products and practices. Put it this way, if you could get your vitamin C from Sunny D or fresh squeezed OJ, which would you prefer?

Cannabidiol (CBD) oil has become increasingly popular as a natural way to help people try to manage pain, reduce inflammation, and cope with anxiety.* Though the number of prescriptions has risen sharply in the United States over the past 20 years, many Americans are trying to limit the number of prescribed drugs they take – instead, searching for all-natural solutions to the aches, pains, and discomfort they begin to face as they age. For many of them, CBD oil is the solution they’ve been looking for. But not all CBD oil is created equal, meaning finding the right CBD oil could just be the most important part of their journey.

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