This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.

I have fibromyalgia going on 18 years & I’m about as physically & mentally beaten down as humanly possible. I’m on fentyl patch 50mcg & oxy. New laws going into effect removed my oxy & fentyl doesn’t cover breakthrough or bad days. I’m barely Mobil @ this point & my options with my doctor is to just raise the fentyl patch to 75mcg. All other options really don’t help since our governor signed into law removing DBL use of narcotics to treat those with severe chronic pain. I would appreciate from educated users respond to the products that work & the forms & dosage.
“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.
CBD Kratom is proud to operate in Chicago, St. Louis, Dallas and Los Angeles! We’re your one-stop shop for CBD oils and edibles, hemp products, various strains of Kratom and lots more. We carry over 45 strains of Kratom and we are always looking to add products. We’ve got CBD gummies, jollies, peanut butter, vape and more. We offer you the largest selection of CBD and Kratom products in Chicago and they’re at affordable prices. Did we mention the staff here at CBD Kratom is just as awesome as the products we carry? If you can’t find what you’re looking for we’ll be sure to help you find it!
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
In order to account for the low CBD content of these hemp plants, manufacturers have to process large volumes of raw material at a time, with the idea of extracting just enough CBD so that they can label their product as a “CBD oil.” While this method is fine in theory, what ultimately ends up happening (unless the manufacturer’s extraction methods are state of the art), is that traces of chemicals cane end up being left over in the final product. These chemicals can potentially contain harsh solvents such as butane, hexane, and propylene glycol, which has been known to break down into carcinogenic (cancer-causing) compounds like formaldehyde and acetaldehyde.
• Filtered (Gold) – This is the most processed of the oil extracts. The plant matter is all filtered out, leaving behind a stronger cannabinoid concentration. This oil is more of a gel texture and will be gold in color with a slightly peppery taste. The serving size will once again be 1-2 grains of rice sized servings per day, or as directed by your physician.
The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
Receptra Naturals CBD products are derived from proprietary CBD rich hemp, grown on family owned and operated farms in Colorado using 100% organic farming practices on select organic soils without the use of pesticides or fungicides.  I got to know the folks at Receptra while dealing with Charlotte's Web Botanicals and continued to stay in contact when they left CW to form Receptra. 
Pesticides, mold, and other contaminants are obviously substances you don’t want to be mainlining into your body, but properly dosed CBD is also crucial. That’s because your body’s response to CBD dosage is bell-curved. Too little and you won’t feel anything; too much and it’ll dampen the impact with reported side effects like lethargy and diarrhea (not chill). Given the lack of research into dosage and the variety of ailments CBD is used for, most people have to find their own “Goldilocks Zone.”
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I appreciate your efforts in writing this article & don’t mean to disparage you, but there’s so much information that goes into this discussion & people need to be prepared ahead of time. One very important note is to make sure that nothing in the CBD will be contraindicated with many prescription medications, especially for diabetes, hypertension, blood thinners & anti-platelets for example. If a company’s website says their formula is a “proprietary blend”, call before you buy, please!
The formulation, however, offers optimized delivery via mucosal membrane permeability in tandem with precision production/formulation methods. Her company, HERBOLOGIE, reduces the particle size of the cannabinoids and immerses them in a matrix of exclusively natural ingredients that work synergistically to enhance absorption through oral membranes. When cannabinoids are transported through membranes and directly into the bloodstream, the phytonutrients are delivered more quickly, and crucially, avoiding first-pass degradation in the liver.  
We are committed to bringing our customers the highest-grade organic cannabis oil products on the market. Our CBD oil is derived from organic hemp plants and is legal in all 50 states. We proudly call ourselves NuLeaf “Naturals” because our cannabis oils are 100% organic, free of additives and preservatives. Every bottle of cannabis oil we provide to our customers has been subjected to rigorous laboratory testing to ensure that it contains the optimal amount of CBD.
For those needing a refresh, CBD or cannabidiol is one of the many compounds, or cannabinoids, found both in cannabis sativa (federally illegal) and industrial hemp (gray area) that has shown preclinical promise in treating anxiety and inflammation. Adding to its therapeutic legitimacy, CBD was recently FDA-approved to be used in an epilepsy drug called Epidiolex making it the first cannabis compound to be federally recognized. Over the last year, CBD’s become the darling of the wellness world, working its way into our juices, facials, creams, and cocktails, purportedly giving people the benefits of cannabis without the THC high. Very chill.
At a molecular level, CBD (short for cannabidiol) is CBD, regardless of which plant it comes from.  The only difference comes from the full extract that is taken from the plants.  Here’s what we mean:  Once the plants are harvested, the lab removes the nutrients, including CBD, from the plants in the form of a gooey extract.  This extract includes the CBD, but also so much more and this gooey extract is what goes into all the CBD products*.  There are actually many cannabinoids other than just cannabidiol (CBD).  Some are CBC, CBG, CBN and even THC.  THC is the compound found in marijuana that causes the “high” or psychotropic or euphoric effect.  As most of us know, marijuana naturally has a fairly high level of this compound.  Hemp naturally has a very low level, so low that no one reports any sort of high when using the extract from hemp.
Watch Out For: Companies that do not have test results or refuse to give them to customers. Also be wary of companies who only test one batch of finished product and then assume that all future batches will be the same – big mistake. Hemp is a product of nature and thus, no two batches will ever be identical – even in the most regulated environment. The company must provide you test results for the actual product you intend to purchase as well as the plant material used to make it – otherwise you are jeopardizing your safety and the medical efficacy of the product.
All the products we carry use the same hemp extract discussed above.  So, it doesn’t really matter which product type you get, you’re still getting the same extract.  And, that’s all that really matters.  So, the decision as to which product type to get comes down mainly to preference.  Do you prefer the specific measuring ability of the drops?  Do you prefer the convenience of a capsule?  These are merely preferences for the most part.
* All CBD products offered on this site are produced in compliance with 21 U.S.C. § 802(16), 21 CFR 1308.11(d)(58 – 7350 Marijuana Extract),  and “Clarification of the New Drug Code (7350) for Marijuana Extract” published by the US Department of Justice, Drug Enforcement Administration, Diversion Control Division https://www.deadiversion.usdoj.gov/schedules/marijuana/m_extract_7350.html
The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.
CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
Called a week later, and was told to email the manager, and was informed he always responds within 1-2 days. Emailed him, and it’s been 2 weeks, since. I called GreenRoads, asked my question, and got an immediate, literate response (multiple hemp sources), as well as a discussion on what differences might or might not occur, and how to check lab sheets for comparison. Switched over to GreenRoads, which seems otherwise comparable in its manufacturing methodology to Elixinol.

Called a week later, and was told to email the manager, and was informed he always responds within 1-2 days. Emailed him, and it’s been 2 weeks, since. I called GreenRoads, asked my question, and got an immediate, literate response (multiple hemp sources), as well as a discussion on what differences might or might not occur, and how to check lab sheets for comparison. Switched over to GreenRoads, which seems otherwise comparable in its manufacturing methodology to Elixinol.
What’s more, CBD vape oils require additional equipment. In order to transform the oil into vapor, you’ll need an e-pen or vaporizer. This means an extra investment on top of the vape oil itself. I therefore recommend that, if you’re a first-time user, you try a more accessible and affordable CBD product type to make sure it’s the right supplement for you, before graduating to vape oil.
CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
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