There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
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“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.

If you’re looking to try the purest CBD oil product around, you can’t go wrong with this Blue Label High-CBD Hemp Oil by Herbal Renewals. This one isn’t for beginners. Make no mistake, this is strong stuff. You will only need the size of a grain of rice taken once or twice daily (the equivalent of roughly 4.1 milligrams of CBD) to feel the desired effects. With that kind of serving size, the three-gram tube will last you a few months of daily use, giving you plenty of CBD goodness. This product is also available in one-gram and ten-gram tubes, along with a six-pack of ten-gram tubes.
Is it full-spectrum? Full-spectrum is the use of the whole hemp plant vs. an isolate which extracts the CBD from the plant. Using marketing terms like “pure” and “all natural,” isolates are sometimes not hemp at all and synthesized in a lab. While the efficacy of full-spectrum is debated in the scientific community, anecdotes and a study in Israel favor full-spectrum. In addition to potential benefits, there’s another reason you should be buying the whole plant: contamination. Chen notes that isolates are harder to trace back to origin and can be straight-up fake. Overseas lab-made isolates are cheaper than domestic versions, making the potential for contamination high. Utah recently grappled with synthetic CBD when 52 people became sick from an isolate. While isolates can be legitimate (FDA-approved Epiliodex is an isolate), you’re going to have to spend more time researching the brand’s products and practices. Put it this way, if you could get your vitamin C from Sunny D or fresh squeezed OJ, which would you prefer?

Mimi says the effective oils are made from the marijuana plant, not hemp. Why are you rating only hemp oils? Are hemp oils the only oils that do not have any THC? The other question that arises is the difference between ml and mg in measuring the strength of these oils. They are quoted as ml, but there is the question of the “density” limit of 95mg? Very confusing.
What’s more, CBD vape oils require additional equipment. In order to transform the oil into vapor, you’ll need an e-pen or vaporizer. This means an extra investment on top of the vape oil itself. I therefore recommend that, if you’re a first-time user, you try a more accessible and affordable CBD product type to make sure it’s the right supplement for you, before graduating to vape oil.
This may seem like a repeat of an earlier question, but while that question related to concentration of CBD in the product, this is simply a question of how much you’re getting in total. Most bottles are labeled in a similar way – “1,000mg CBD Oil” or “1,000mg Hemp Extract” – which generally means the entire bottle contains a total of 1,000mg of CBD.
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