The compounds found within cannabis (known as cannabinoids) are very similar to the ones produced naturally by our bodies. These cannabinoids have been observed to relieve the symptoms of various conditions by attaching themselves to particular receptors in the brain, thereby blocking or boosting certain signals. This can help bring calm to an otherwise stressful situation.

Mimi says the effective oils are made from the marijuana plant, not hemp. Why are you rating only hemp oils? Are hemp oils the only oils that do not have any THC? The other question that arises is the difference between ml and mg in measuring the strength of these oils. They are quoted as ml, but there is the question of the “density” limit of 95mg? Very confusing.

If you are vaporizing CBD-dominant strains of cannabis, bioavailability is through the alveoli, tiny sacs in the lungs, clarifies Kilham. If you are taking CBD strain capsules, he suggests eating some fat or oil, like a handful of nuts or some full-fat yogurt, to improve absorption and bioavailability. Cannabinoids are fat-loving molecules. They are taken up readily into the small intestine with a bit of dietary fat.
You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.

There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
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Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
Hello! I do not have a response regarding what you should take, BUT want you to know I am exactly where you are! Three level lumbar fusion on 02/05/18, no staples thank goodness (they used glue), but am weaning myself off of pain meds ( I don’t like their side effects, as you stated). Weaning off the pain meds leaves me susceptible to flare ups when I do my PT or go for my daily walks three times a day. I surely hope someone answers the question you posed, as I would like to know! Wishing you the best of luck in your recovery! Stay strong!

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It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.
Tinctures are ideal for CBD novices, as they’re not always as strong as other CBD product types. If you know how much CBD you require and you’re after a higher concentration, a regular CBD tincture is unlikely to deliver the goods. However, this is beginning to change as companies experiment with higher concentrations. In the meantime, consider a vape oil, paste, or concentrate to enjoy a stronger CBD experience.

Research on CBD and anxiety has generally looked at cannabis as a whole product, not as CBD as a standalone compound. Some studies suggest that it can help with anxiety: like this 2011 study that suggests CBDcan reduce social anxiety or this 2015 review that says CBD could be promising for many forms of anxiety. It’s also important to consider whether the CBD comes from the cannabis plant and therefore may include THC, a cannabinoid that for some, induces anxiety. Read our comprehensive article on CBD and anxiety, here.
CBD testing shouldn’t just tell you what’s in a CBD oil, which is usually CBD along with a carrier oil like grapeseed oil and maybe some other essential oils for flavor. It should also let you know what’s not in the package. Thorough testing can confirm that the oil you’re buying is not only real CBD, but that it’s free of contaminants like pesticides and synthetic CBD substitutes.
Called a week later, and was told to email the manager, and was informed he always responds within 1-2 days. Emailed him, and it’s been 2 weeks, since. I called GreenRoads, asked my question, and got an immediate, literate response (multiple hemp sources), as well as a discussion on what differences might or might not occur, and how to check lab sheets for comparison. Switched over to GreenRoads, which seems otherwise comparable in its manufacturing methodology to Elixinol.
Some industry insiders argue that organic, pharmaceutical-grade ethanol, which is a grain alcohol, is optimal and eliminates certain toxins and residues in the raw plant material itself. But others say that while this extraction method yields a high amount of cannabinoids and is GRAS (Generally Recognized as Safe) for human consumption, it destroys the plant’s waxes, leading to a less potent oil.
I have also called a couple places to get some input about what we may need, but they all said they cannot give advice. Then HOW do we know what to get. As for MOST of us, we are by no means well off. Quite the opposite, in fact. So to keep “trying” a bunch of different ones is not an option. Blue Bird in CO give discounts to low income, so would like to use their products if possible.
At a molecular level, CBD (short for cannabidiol) is CBD, regardless of which plant it comes from.  The only difference comes from the full extract that is taken from the plants.  Here’s what we mean:  Once the plants are harvested, the lab removes the nutrients, including CBD, from the plants in the form of a gooey extract.  This extract includes the CBD, but also so much more and this gooey extract is what goes into all the CBD products*.  There are actually many cannabinoids other than just cannabidiol (CBD).  Some are CBC, CBG, CBN and even THC.  THC is the compound found in marijuana that causes the “high” or psychotropic or euphoric effect.  As most of us know, marijuana naturally has a fairly high level of this compound.  Hemp naturally has a very low level, so low that no one reports any sort of high when using the extract from hemp.

CBD oil is similar to other products in that it is capable of being “watered down.” Some companies will try to eke out a higher profit margin by fooling their customers into thinking they’re getting more for less. It is important to pay attention to the concentration level of the CBD oil you’re buying in order to ensure you’re getting what you’re paying for. Although concentrations of CBD can vary quite a bit across the broad range of CBD products, a quality product will start off having somewhere between 250mg to 1,000mg per fluid ounce. This matters because if you were to purchase a 4 ounce bottle that contained 250mg of CBD, your concentration would be a mere 62.5 mg of CBD per ounce – hardly enough to reap the full benefits of CBD. It’s always important to look at the concentration level of the CBD you’re buying.

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