“The need for enhanced bioavailability of the CBD phytonutrient is paramount”, adds Moriarity, “but tricky to accomplish without synthetic chemicals.” Most CBD products do not offer any bioavailability optimization, so 90 percent of the CBD is lost to first-pass effect, a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches systemic circulation.
The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here
We strive to carry only the best Hemp Extract and CBD Oil products for you and your loved ones. There are many brands and styles available throughout the marketplace. However, we purposely do not carry all brands that are made. We carry only the finest Extracts, Tinctures, CBD Vape Oil, and CBD Dabs-Wax products for our customers. We want to make sure that if you come to buy cannabinoid products from us, you can rest assured that what you’re getting is truly the best of the best.
I cannot personally vouch for most of the brands on Amazon currently vs. most of the merchants on our page here, but I include Amazon as a resource for the folks that are comfortable shopping via that platform. You can also find my beginners guide, The Cannabis Oil Companion on Amazon in both paperback and Kindle. *We have been having some issues with our Amazon widget not displaying below intermittently in certain browsers, trying to troubleshoot this behavior, we apologize if this is not rendering for you. There is also a text link to Amazon's hemp oil section listed below.
To add to the challenges, brands in the CBD space are struggling to verify their own products. Laura White, founder of Soul Addict, started a CBD line after she found it helped her with crippling anxiety. Wanting to create a reliable product in both purity and potency, she’d test on top of the farm’s tests and kept running into the same problem: The lab results didn’t match. When White finally found a farm that had accurate tests, she’d partner with them. A few years later, Soul Addict now sources all its CBD through small, family-run farms in Colorado and White is in the process of integrating her own crops from North Carolina. The lesson she learned? Brands should be constantly testing their product to verify their farms’ reports.
CBD capsules are all about convenience. They’re portable, discreet, easy to take, of a higher concentration, and have no taste whatsoever. Because of this, you’ll usually end up paying a little more per serving than some other CBD product types. If price is a concern, consider trying CBD concentrates. They’re the most pure form of CBD oil and are also the most cost-effective.